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        TEST NAME		  	  RESULT	UNITS             REF. RANGE
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     Vitamin B12 (Cynocobalamin)	  <  60             pg/ml		(208 - 963.5)	

Comments :-
Vitamin B12, a member of the corrin family of compounds, is implicated in the formation of myelin, and along with Folate, is required for DNA synthesis. The most prominent source of B12 for humans is meat, while untreated fresh water can also be a source.
Up to 40 - 50 % of serum corrins may be physiologically inactive B12 analogues. These analogues serve no useful function and m,ay compete with B12 for serum B12 binding capacity. The archetypical analogue, combinamide, is not bound by the primary binding protein specific for ileal B12 uptake.
Megaloblastic Anaemia, characterized by elevated MCV, has been found to be due to B12 deficiency, a major cause being pernicious Anaemia due to poor B12 uptake resulting in below normal serum levels. Other conditions related to low B12 levels include iron deficiency, normal near-term pregnancy, vegetarianism, partial gastrectomy, oleal damage, oral contraceptives, parasitic infestation, pancreatic deficiency, treated epilepsy and advancing age. The correlation of serum B12 levels and Megalobastic Anaemia, however, is not always clear - some patients with high MCV may have normal B12 levels, while some individuals with B12 deficiency may not have Megaloblastic Anaemia. Disorders like renal Failure, liver disease and Myeloproliferative diseases may have elevated vitamin B12 levels.